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Introducing the First GLP-1 Weight Loss Pill

Professional, evidence-backed care designed to help you achieve sustainable weight results and improve your health.

  • Same proven GLP-1 science, delivered as a daily tablet
  • Up to ~17% body weight loss in clinical trials
  • No needles, no fridge — pocket-sized treatment
  • Switching support for existing GLP-1 patients
Discreet next day delivery
100% UK-based pharmacy
Free advice and support
We're rated 4.7 out of 5

GLP-1 Tablets vs GLP-1 Injections

Same GLP-1 hormone pathway, two delivery formats — see how a once-daily tablet stacks up against the weekly injection.

TREATMENT
TYPE
FREQUENCY
AVG. WEIGHT LOSS
Pill NEW
Type
Pill
Frequency
Once daily
Avg. Weight Loss
Up to ~17%
Injection
Type
Pen
Frequency
Once weekly
Avg. Weight Loss
Up to ~20%

Your weight-loss journey

Treatments made to change your weight, mindset and life.
0-3 Months
Simple Assessment

Simple Assessment

It can take up to 8-9 weeks to feel the full effects of your medication, but you’ll gradually increase your dose as your body adjusts and your hunger reduces.

3-6 Months
Lose 5-22.5% Bodyweight

Lose 5-22.5% Bodyweight

By continuing to move forward with our programme, you’ll lose at least 10% of your body weight by the end of month 6.

6-12 Months +
Build Lasting change

Build Lasting change

You and your coach will chart your course to lasting weight loss, with a plan for sticking to your new healthy habits.

Get the weight care you deserve

Am I eligible? ›
Advanced treatments

Advanced treatments

Clinically supported treatments customised to meet individual health needs.

Weight loss professionals

Weight loss professionals

Expert clinical support whenever you need it, ensuring safe and trusted care.

Maintenance plans

Maintenance plans

Maintenance plans provide patients with a safe and effective way to sustain their weight loss after reaching their target.

What are oral GLP-1 tablets?

GLP-1 (glucagon-like peptide-1) receptor agonists are prescription medicines used in weight management. Some GLP-1 medicines are currently available as injections following assessment by a clinician.

Oral GLP-1 tablets are tablet formulations being developed and studied for weight management. These medicines work by mimicking the GLP-1 hormone, which can help regulate appetite and food intake.

Treatment suitability, availability and prescribing decisions are determined by a clinician following an appropriate consultation.

What are they?

  • Tablet-based weight loss treatments
  • Contain a GLP-1 receptor agonist (the same active ingredient as Wegovy)
  • Taken once daily, rather than once weekly by injection
  • Clinically tested with results comparable to injectable options

Why are people interested?

  • A non-injectable alternative for those who prefer not to use a pen
  • Easier to fit into everyday life for some people
  • No refrigeration or injection equipment required
  • The same clinically-led approach, in a simpler format

Tablets vs injections: which is right for you?

Oral GLP-1 tablets and injectable GLP-1 treatments are both effective, clinically-proven options. The right choice depends on your personal preferences and circumstances. Here is a quick comparison:

Oral GLP-1 Tablets
Weekly Injections
Format
Once-daily tablet
Once-weekly injection (pen)
Clinically proven
Yes
Yes
Weight loss (avg)
Up to ~17%
Up to ~20%
Ongoing clinical support
Yes – always included with 123 Meds
Yes – always included with 123 Meds
Best for
People who prefer not to inject
People who want treatment now
Oral GLP-1 Tablets
Format Once-daily tablet
Clinically proven Yes
Weight loss (avg) Up to ~17%
Ongoing clinical support Yes – always included with 123 Meds
Best for People who prefer not to inject
Weekly Injections
Format Once-weekly injection (pen)
Clinically proven Yes
Weight loss (avg) Up to ~20%
Ongoing clinical support Yes – always included with 123 Meds
Best for People who want treatment now

* Averages from clinical trials in controlled settings alongside diet and lifestyle support. Individual results will vary.

* The two trials used different designs and durations and cannot be directly compared with each other.

* Both treatments are not yet available in the UK. Availability is subject to regulatory approval. Both expected in 2026.

Frequently asked questions

Everything you need to know about the oral GLP-1 pill and joining the waitlist. Can't find what you're looking for? Our clinical team is here to help.

Get in touch
Clinical Assistance

GLP‑1 tablets are prescription medicines that mimic a natural hormone involved in appetite and blood sugar regulation. They are used to support weight management in eligible adults as part of a wider treatment plan that includes diet and lifestyle changes

These medicines work by helping you feel fuller for longer, reducing hunger and slowing stomach emptying. This can help lower calorie intake over time.

They work in a similar way to injectable GLP‑1 treatments, but they are taken as a tablet instead of an injection. The active ingredient and dosing schedule may differ depending on the specific medicine prescribed.

GLP‑1 tablets are not suitable for everyone. A clinician will assess factors such as your BMI, medical history, current medications and any weight-related health conditions before prescribing treatment.

Most oral GLP‑1 tablets are taken once daily on an empty stomach with a small amount of water. You usually need to wait before eating, drinking or taking other medicines. Always follow the instructions provided with your prescription.

Oral GLP-1 tablets are highly effective prescription medicines under clinical development for sustainable weight management. They mimic hormones in your body to reduce appetite and manage cravings.

The most common side effects are digestive and may include nausea, diarrhoea, constipation, vomiting or stomach discomfort. These are often mild and may improve as your body adjusts to treatment.

GLP‑1 tablets have been evaluated by medicines regulators and are prescribed by qualified healthcare professionals. Like all medicines, they carry potential risks and side effects, so they should only be used under medical supervision.

Possibly, but some medicines can interact with GLP‑1 treatments. Your prescriber will review your current medications and advise whether treatment is appropriate for you.

Yes. GLP‑1 tablets are most effective when used alongside a reduced-calorie diet, regular physical activity and sustainable lifestyle habits.

Follow the instructions in your patient leaflet or ask your prescriber for advice. Do not take a double dose unless specifically instructed to do so.

Only use regulated UK pharmacies like 123 Meds that require a medical assessment before prescribing. Avoid unregulated sellers or social media offers.

With years of experience under our belts, our medical team has got you covered!​

 

Dr Adnan Malik

Medical Advisor

MBBS, BMedSci (Hons), MRCS (Eng)

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Kishan Kotecha

Superintendent Pharmacist

MPharm IP GPhC: 2063786

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Priyesh Bhogaita

Pharmacy Operations Manager

BSc (Hons)

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